Table 3. Randomized Controlled Trials Investigating the Use of Neoadjuvant Chemotherapy Prior to Radical Prostatectomy or Adjuvant Chemotherapy Following Radical Prostatectomy in Patients with High-risk Localized Prostate Cancer

All PSA values are quoted in ng/ml.
*See [16].
‡See [78].
ADT: Androgen-deprivation therapy; bPFS: Biochemical progression-free survival; CALGB: Cancer and Leukemia Group B; GETUG: Groupe d'Étude des Tumeurs Uro-Génitales; LHRH-a: Luteinizing hormone-releasing hormone agonist; OS: Overall survival; PSA: Prostate-specific antigen; RP: Radical prostatectomy; RT: Radiotherapy; SPCG: Scandinavian Prostate Cancer Group; SWOG: Southwest Oncology Group; VA CSP: Veterans Affairs Cooperative Studies Program.

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